Home

Current Issue

Archives

Guidelines for Authors

Classified Ads

Subscriptions

Contact Info

Email Alert Service

Links

Primary Cutaneous B Cell Lymphoma During Methotrexate Therapy for Rheumatoid Arthritis

ADEL G. FAM, BAYARDO PEREZ-ORDONEZ, and KEVIN IMRIE

ABSTRACT.

A patient with rheumatoid arthritis developed a reversible, primary cutaneous, large B cell lymphoma during prolonged methotrexate (MTX) treatment. Regression of the skin lesions after discontinuation of the drug suggested a close relationship to MTX. Increased clinical awareness, discontinuation of MTX, and close observation are important in the initial management of this rare lymphoproliferative disorder. (J Rheumatol 2000;27:1546–9)

Key Indexing Terms:

PRIMARY CUTANEOUS LYMPHOMA
METHOTREXATE
RHEUMATOID ARTHRITIS