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Case Report - Thrombosis Associated with the Prothrombin G®A20210 Mutation in Behçet’s Disease

CARLO SALVARANI, KENNETH CALAMIA, MAURO SILINGARDI, ANGELO GHIRARDUZZI, and IGNAZIO OLIVIERI

ABSTRACT. We describe 2 cases of Behçet’s disease (BD) and thrombosis who were heterozygous for the prothrombin G®20210 mutation. In one case, progressive uncontrolled thromboses led to death. Case-control studies are needed to support the hypothesis of the role of the prothrombin A20210 allele as a risk factor for venous thrombosis in some patients with BD. (J Rheumatol 2000;27:515–6)

Key Indexing Terms:

BEHCET’S DISEASE
PROTHROMBIN
THROMBOSIS



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