Case Report

Sensory Neuropathy Revealing Necrotizing Vasculitis During Infliximab Therapy for Rheumatoid Arthritis

PASCAL RICHETTE, PHILIPPE DIEUDÉ, JOËL DAMIANO, CATHERINE LACROIX, FRÉDÉRIC LIOTÉ, PHILIPPE ORCEL, and THOMAS BARDIN

ABSTRACT.

We describe 2 patients with severe erosive rheumatoid arthritis and rheumatoid vasculitis, respectively, in whom infliximab therapy was associated with peripheral neuropathy due to necrotizing vasculitis in one patient and to progression of preexisting mononeuritis multiplex in the other. (J Rheumatol 2004;31:2079-81)

Key Indexing Terms:

RHEUMATOID VASCULITIS
RHEUMATOID ARTHRITIS
INFLIXIMAB
VASCULITIS
ANTI-TUMOR NECROSIS FACTOR

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From the Fédération de Rhumatologie, Hôpital Lariboisière, Paris, France.

P. Richette, MD, PhD; P. Dieudé, MD; J. Damiano, MD; C. Lacroix, MD; F. Lioté, MD, PhD; P. Orcel, MD, PhD; T. Bardin, MD.

Address reprint requests to Dr. P. Richette, Fédération de Rhumatologie, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France. E-mail: pascal.richette@lrb.ap-hop-paris.fr

Submitted September 26, 2003; revision accepted May 4, 2004.

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