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Case Report
Chronic Diffuse Sclerosing Osteomyelitis Treated with Risedronate
STEPHEN A. WRIGHT, AULEEN M. MILLAR, STEVE M. COWARD, and MICHAEL B. FINCH ABSTRACT. We describe a 21-year-old woman with chronic diffuse sclerosing osteomyelitis (CDSO) of the left femur. The patient presented with shortening of the left leg and intractable pain that was unrelieved with conventional analgesia. Radiological imaging and open bone biopsy confirmed the diagnosis of chronic diffuse sclerosing osteomyelitis. Treatment with risedronate was commenced and a dramatic response in the patient's symptoms and biochemical markers of bone turnover was observed. To our knowledge this is the first case of CDSO treated successfully with risedronate. (J Rheumatol 2005;32:1376-8) Key Indexing Terms:
CHRONIC DIFFUSE SCLEROSING OSTEOMYELITIS From the Department of Rheumatology, Musgrave Park Hospital, Belfast, Northern Ireland. S.A. Wright, MB (Hons), MRCP, Rheumatology Specialist Registrar; A.M. Millar, MB, Rheumatology Senior House Officer; S.M. Coward, MSc, Biomedical Scientist; M.B. Finch, MD, FRCPI, FRCP, Consultant Rheumatologist. Address reprint requests to Dr. S. Wright, Department of Rheumatology, Musgrave Park Hospital, Belfast BT9 7JB, Northern Ireland. E-mail: stephen@wright866.fsnet.co.uk Accepted for publication December 13, 2004. |