Case Report

Primary Cutaneous Nocardia otitidiscaviarum Infection in a Patient with Rheumatoid Arthritis Treated with Infliximab

SYLVIE FABRE, CHRISTELLE GIBERT, CATHERINE LECHICHE, CHRISTIAN JORGENSEN, and JACQUES SANY

ABSTRACT.

Anti-tumor necrosis factor-a (anti-TNF-a) therapy strategies result in significant clinical benefits in patients with rheumatoid arthritis, but with an increased rate of serious infectious diseases. We describe a patient receiving infliximab who developed a primary cutaneous Nocardia otitidiscaviarum infection after a skin injury. (J Rheumatol 2005;32:2432-3)

Key Indexing Terms:

SKIN INFECTION
NOCARDIA OTITIDISCAVIARUM
RHEUMATOID ARTHRITIS
INFLIXIMAB
ANTI-TUMOR NECROSIS FACTOR-a

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From the Department of Immuno-Rheumatology, Centre Hospitalier Universitaire Lapeyronie, Montpellier, France.

S. Fabre, MD; C. Gibert, MD, Department of Immuno-Rheumatology; C. Lechiche, MD, Department of Infectious Disease; C. Jorgensen, MD, PhD; J. Sany, MD, PhD, Department of Immuno-Rheumatology.

Address reprint requests to Dr. S. Fabre, Department of Immuno-Rheumatology, Centre Hospitalier Universitaire Lapeyronie, 34 295 Montpellier, cedex 5, France.

Accepted for publication June 28, 2005.

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