Abstract: Parvovirus B19: Another Agent Associated with Remitting Seronegative Symmetrical Synovitis with Pitting Edema

Parvovirus B19: Another Agent Associated with Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS₃PE)?

CARLOS E. PERANDONES, INES COLMEGNA, and ROBERTO M. ARANA

ABSTRACT.

A number of conditions have been associated with remitting seronegative symmetrical synovitis with pitting edema (RS₃PE) and the controversy of whether this should be considered a syndrome rather than a disease continues. There are few reports on the role of infectious agents in the etiology of RS₃PE, and human parvovirus B19 has not previously been linked to this syndrome. We describe a patient with RS₃PE syndrome in association with positive serology and viremia for parvovirus B19. A 9-year followup failed to uncover another cause for RS₃PE. (J Rheumatol 2005;32:389-90)

Key Indexing Terms:

REMITTING SERONEGATIVE SYMMETRICAL SYNOVITIS WITH PITTING EDEMA
McCARTY SYNDROME
PARVOVIRUS B19
VIRAL ARTHRITIS

From the Division of Rheumatology and Immunology, Department of Internal Medicine, CEMIC, Buenos Aires, Argentina.

C.E. Perandones, MD; I. Colmegna, MD; R.M. Arana, MD, Head, Division of Rheumatology and Immunology.

Address reprint requests to Dr. C.E. Perandones, Peña 2034 (Apt. A1) 1126, Buenos Aires, Argentina. E-mail: cperandones@cemic.edu.ar

Submitted May 17, 2004; revision accepted September 15, 2004.