D-Hormones for Prevention of Bone Loss After Organ Transplant

PHILIP N. SAMBROOK

ABSTRACT.

In addition to bisphosphonates, D-hormones appear to be effective agents in the prevention of post-transplant osteoporosis. In this article studies on D-hormone agents for prevention of post-transplant bone loss are reviewed. Potential reduction in immunosuppressive requirements with D-hormone is an additional consideration. Based upon available evidence, prophylaxis should involve a bisphosphonate, with D-hormone considered as adjunctive or alternative therapy. (J Rheumatol 2005;32 Suppl 76:41-43)

Key Indexing Terms:

TRANSPLANTATION
OSTEOPOROSIS
VITAMIN D

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From the Institute of Bone and Joint Research, University of Sydney, Sydney, Australia.

P.N. Sambrook, MD, Professor of Rheumatology.

Address reprint requests to Prof. P.N. Sambrook, Royal North Shore Hospital, St. Leonards, Sydney, New South Wales 2065, Australia.

E-mail: sambrook@med.usyd.edu.au

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