Case Report

Sarcoidosis-like Reaction Related to Propionibacterium acnes and Immune Restoration Syndrome in HIV Infection

KHALIL EL KAROUI, FANNY LANTERNIER, ANNE BRUNET, PHILIPPE BLANCHE, and LOÏC GUILLEVIN

ABSTRACT.

Propionibacterium acnes is thought to be a potential triggering agent of sarcoidosis. We describe a woman who developed chronic meningitis with sarcoid-like multisystemic involvement under treatment for human immunodeficiency virus infection. P. acnes was isolated from cerebrospinal fluid. We assume that P. acnes might have triggered this sarcoid-like reaction with meningitis, as a consequence of an immune reconstitution. (J Rheumatol 2007;34:2495-6)

Key Indexing Terms:

SARCOIDOSIS
AIDS
PROPIONIBACTERIUM ACNES

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From the Department of Internal Medicine, Centre national de référence pour les vascularites et la sclérodermie, Hôpital Cochin, Université Paris-Descartes, Paris, France.

K. El Karoui, MD; F. Lanternier, MD; A. Brunet, MD; P. Blanche, MD; L. Guillevin, MD.

Address reprint requests to Prof. P. Blanche, Department of Internal Medicine, Hôpital Cochin, Université Paris-Descartes, 27 rue du Faubourg Saint-Jacques, Paris, France. E-mail: philippe.blanche@cch.aphp.fr

Accepted for publication July 27, 2007.

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