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Developing a Magnetic Resonance Imaging Scoring System for Peripheral Psoriatic Arthritis
FIONA McQUEEN, MARISSA LASSERE, PAUL BIRD, ESPEN A. HAAVARDSHOLM, CHARLES PETERFY, PHILIP G. CONAGHAN, BO EJBJERG, HARRY GENANT, PHILIP O'CONNOR, PAUL EMERY, and MIKKEL ØSTERGAARD ABSTRACT. We describe the first steps in developing an OMERACT magnetic resonance imaging (MRI) scoring system for peripheral psoriatic arthritis (PsA). A preexisting MRI dataset (finger joints) from 10 patients with PsA was scored by 4 readers for bone erosion, bone edema, synovitis, tendinopathy, and extracapsular features of inflammation (including enthesitis) according to specified criteria. Scoring reliability between readers was moderate to high for bone edema and erosion, but lower for soft tissue inflammation. Measures to improve reliability for future exercises will include reviewing definitions of pathological features and prior reader calibration. (J Rheumatol 2007;34:859–61) Key Indexing Terms:
PSORIATIC ARTHRITIS From the Department of Rheumatology, Auckland University, Auckland, New Zealand; Department of Rheumatology, St. George Hospital, University of New South Wales, Sydney, Australia; Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Synarc Inc., University of California, San Francisco, California, USA; Academic Unit of Musculoskeletal Disease, University of Leeds; Department of Radiology, Chapel Allerton Hospital, Leeds, UK; and Copenhagen University Hospitals at Herlev and Hvidovre, Copenhagen, Denmark. Travel for Dr. McQueen to attend OMERACT 8 in Malta was assisted by grants awarded by the Auckland Medical Research Foundation and the Maurice and Phyllis Paykel Trust. F. McQueen, MD, FRACP, Associate Professor in Rheumatology, Department of Rheumatology, Auckland University; M. Lassere, MB, BS, Grad Dip Epi, PhD, FRACP, FAFPHM, Associate Professor in Medicine, Department of Rheumatology, St. George Hospital, University of NSW; P. Bird, BMed (Hons) FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of NSW; E.A. Haavardsholm, MD, Research Fellow, Diakonhjemmet Hospital, University of Oslo; C. Peterfy, MD, PhD, Chief Medical Officer, Synarc Inc.; P.G. Conaghan, MB BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Academic Unit of Musculoskeletal Disease, University of Leeds; B. Ejbjerg, MD, PhD, Senior Registrar, Copenhagen University Hospital at Herlev; H. Genant, MD, FACR, FRCR, Professor of Radiology, University of California, San Francisco; P. O'Connor, MB BS, MRCP, FRCR, Consultant Skeletal Radiologist, Department of Radiology, Chapel Allerton Hospital; P. Emery, MA, MD, FRCP, ARC Professor in Rheumatology, Academic Unit of Musculoskeletal Disease, University of Leeds; M. Østergaard, MD, PhD, DMSc, Professor in Rheumatology/Arthritis, Copenhagen University Hospitals at Herlev and Hvidovre. Address reprint requests to Dr. F. McQueen, Department of Molecular Medicine and Pathology, University of Auckland, PO Box 92019, Auckland, New Zealand. E-mail: f.mcqueen@auckland.ac.nz
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