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The Prevalence of Diffuse Idiopathic Skeletal Hyperostosis in an Outpatient Population in
the Netherlands
L. ANNELOES WESTERVELD, HENRIETTE M.E. QUARLES van UFFORD, JORRIT-JAN VERLAAN, and F. CUMHUR ONER
ABSTRACT. Methods. Chest radiographs of 501 patients (age > 50 yrs) referred to our institution by general practitioners for non-spine-related conditions were reviewed. DISH was established according to defined criteria; 3-level involvement was defined as pre-stage DISH. Logistic regression analysis was used to investigate the influence of age and sex on the prevalence of DISH. Results. The overall prevalence of DISH was 17.0% (95% CI 13.7–20.3). A significant increase with age was observed (odds ratio 1.03, 95% CI 1.01–1.05; p = 0.006). The odds ratio of male sex was 1.85 (95% CI 1.20–2.86; p = 0.006). The individual predicted probability of developing DISH was 32.1% in 80-year-old men and 16.9% in women of the same age. Pre-stage DISH was found in 4.6% of the individuals and was more frequent in women. Conclusion. The prevalence of DISH in this outpatient cohort was 17.0%, which is high compared to recent reports. Age and sex were significantly related to the presence of DISH, suggesting that men and older individuals have a higher probability of developing DISH. (First Release June 1 2008; J Rheumatol 2008;35:1635–8) Key Indexing Terms:
DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS
From the Department of Orthopaedics and the Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands. L.A. Westerveld, MD, Department of Orthopaedics; H.M.E. Quarles van Ufford, MD, Department of Radiology; J.J. Verlaan, MD, PhD; F.C. Oner, MD, PhD, Department of Orthopaedics. Address reprint requests to Dr. L.A. Westerveld, University Medical Center Utrecht, Department of Orthopaedics, Heidelberglaan 100, Huispostnummer G05.228, Utrecht 3584 CX, The Netherlands. E-mail: l.a.westerveld@umcutrecht.nl Accepted for publication March 14, 2008. |
