Proceedings of an International Workshop on Osteoarthritis Outcomes
Indianapolis, Indiana, USA
December 13–14, 2002
Introduction: Proceedings of an International Workshop on Osteoarthritis Outcomes
K.D. Brandt .........1
Obesity and Vocational and Avocational Overload of the Joint as Risk
Factors for Osteoarthritis D.T. Felson .........2
Do Risk Factors for Incident Hip Osteoarthritis (OA) Differ from Those for
Progression of Hip OA? M.C. Hochberg .........6
Who Gets Osteoarthritis and Why? E.L. Radin .........10
Specific Gene Defects Leading to Osteoarthritis R.W. Moskowitz .........16
How Important Are Genetic Factors in Osteoarthritis? M. Doherty .........22
Markers of Altered Metabolism in Osteoarthritis L.S. Lohmander .........28
Radiographic Issues in Imaging the Progression of Hip and Knee Osteoarthritis
E. Vignon .........36
Cartilage Oligomeric Matrix Protein as a Marker of Osteoarthritis J.M. Jordan .........45
Relationship Between Symptoms and Structural Change in Osteoarthritis.
What Are the Important Targets for Osteoarthritis Therapy? P.A. Dieppe .........50
Recent Approaches to Understanding Osteoarthritis Pain L.A. Bradley .........54
Pushing the Limits of Patient-Oriented Outcome Measurements in the
Search for Disease Modifying Treatments for Osteoarthritis M.H. Liang .........61
Outcome Measures for Clinical Trials of Disease Modifying
Osteoarthritis Drugs in Patients with Hip Osteoarthritis M. Dougados .........66
Inflammation in Osteoarthritis S.B. Abramson .........70
The Importance of Subchondral Bone in the Progression of Osteoarthritis D.B. Burr .........77
Impact of Exercise on Osteoarthritis Outcomes M.A. Minor .........81
The Role of Proprioceptive Deficits, Ligamentous Laxity, and Malalignment
in Development and Progression of Knee Osteoarthritis L. Sharma .........87