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VOLUME 33: NO. 4 APRIL 2006
Editorials
How Meaningful Is Our Evaluation of Meaningful Change in Osteoarthritis?

G.A. Hawker, M.A.M. Gignac.........639
What Are Open-Label Extension Studies For?

W.J. Taylor, M. Weatherall .........642
Allogeneic Bone Marrow Transplantation for Autoimmune Disease The Jury Is Still Out

A. Tyndall.........644
Articles
Antibodies to Viral Citrullinated Peptide in RA
 C. Anzilotti, G. Merlini, F. Pratesi, C. Tommasi,
D. Chimenti, P. Migliorini .........647
Paraarticular Trabecular Bone Loss at the Ultradistal Radius and Increased Arterial Stiffening in Postmenopausal Patients with RA
 K. Tanaka, M. Inaba, H. Goto, et al .........652
Comparison of 2 Doses of Etanercept (50 vs 100 mg) in Active RA: A Randomized Double Blind Study
 A.K. Johnsen, M.H. Schiff, P.J. Mease, et al .........659
Community-Based Evaluation of Etanercept in Patients with RA
 P. Farahani, M. Levine, K. Gaebel,
E.C.Y. Wang, N. Khalidi .........665
Evidenced-Based Medicine Is Affordable: The Cost-Effectiveness of Current Compared with Optimal Treatment in RA and OA
 G. Andrews, L. Simonella,
H. Lapsley, K. Sanderson, L. March .........671
Treatment of RA Patients with Abatacept and MTX Significantly Improved Health-Related Quality of Life
 P. Emery, M. Kosinski, T. Li, et al .........681
Prevalence and Associated Factors for Falls in Women with Established Inflammatory Polyarthritis
 A.E. Oswald, S.R. Pye, T.W. O'Neill, et al .........690
Prevalence and Clinico-Serological Correlations of Anti-a-Enolase, Anti-C1q, and Anti-dsDNA Antibodies
in Patients with SLE
 M. Mosca, D. Chimenti, F. Pratesi, et al.........695
ACE Insertion/Deletion Polymorphism and SLE:
A Metaanalysis
 Y.H. Lee, Y.H. Rho, S.J. Choi,
J.D. Ji, G.G. Song .........698
Relationship Between IL-6 Promoter Polymorphism at Position 174, IL-6 Serum Levels, and the Risk of Relapse/Recurrence in PMR
 L. Boiardi, B. Casali, E. Farnetti, et al .........703
Myelopathies Secondary to SS: Treatment with Monthly IV Cyclophosphamide Associated with Corticosteroids
 J. de Seze, S. Delalande, A-L. Fauchais, et al .........709
Continued Inhibition of Radiographic Progression in Patients with PsA Following 2 Years of Treatment with Etanercept
 P.J. Mease, A.J. Kivitz, F.X. Burch, et al .........712
Is Sulfasalazine Effective in AS? A Systematic Review of Randomized Controlled Trials
 J. Chen, C. Liu .........722
The Cost-Effectiveness of Infliximab (Remicade®) in the Treatment of AS in Canada
 G. Kobelt, P. Andlin-Sobocki,
W.P. Maksymowych.........732
HFE Gene Mutations Are Associated with OA in
the Index or Middle Finger MCP Joints
 G.J. Carroll .........741
Do Exercise and Self-Management Interventions Benefit Patients with OA of the Knee? A Metaanalytic Review
 L. Devos-Comby, T. Cronan, S.C. Roesch.........744
What Do OA Health Outcome Instruments Measure? Impairment, Activity Limitation, or Participation Restriction?
 B. Pollard, M. Johnston, P. Dieppe.........757
Measuring the Outcome of Health Resort Programs
 M. Weigl, T. Ewert, J. Kleinschmidt, G. Stucki .........764
Physician Control of Needle and Syringe During Aspiration-Injection Procedures with the New Reciprocating Syringe
 W.L. Sibbitt Jr, R.R. Sibbitt, A.A. Michael, et al.........771
Gastrointestinal Prophylactic Therapy Among Patients with Arthritis Treated by Rheumatology Specialists
 E. Benito Garcia, K. Michaud, F. Wolfe .........779
Increased Expression of N-Methyl-D-Aspartate Receptor Subunit 2D in the Skin of Patients with FM
 S-H. Kim, T.J. Jang, I.S. Moon.........785
Pediatric Rheumatology
Preliminary Validation of Clinical Remission Criteria Using the OMERACT Filter for Select Categories of JIA
 C.A. Wallace, A. Ravelli, B. Huang, E.H. Giannini .........789
A Case-Control Sleep Study in Children with Polyarticular JRA
 C.M. Passarelli, S. Roizenblatt,
C.A. Len, et al .........796
Corticosteroid Treatment of Refractory Kawasaki Disease
 B.A. Lang, R.S.M. Yeung, K.G. Oen, et al .........803
Recurrent Transient Synovitis of the Hip in Childhood. Longterm Outcome Among 39 Patients
 Y. Uziel, Y. Butbul-Aviel, J. Barash, et al .........810
Case Reports
Twenty-year Remission of RA in 2 Patients After Allogeneic Bone Marrow Transplant
 R.M. Lowenthal, H. Francis, D.S. Gill .........812
Desensitization to Hydroxychloroquine Experience of 4 Patients
 M. Mates, S. Zevin, G.S. Breuer, P. Navon,
G. Nesher.........814
Mycobacterium marinum Arthritis Mimicking RA
 A. Lam, W. Toma, N. Schlesinger.........817
Images in Rheumatology
Intrathoracic Arteritis: A Paraneoplastic Presentation
of Malignant Melanoma
 S.R. Johnson, G. Gardiner, L.A. Rubin.........820
Chronic Infantile Neurological Cutaneous and
Articular Syndrome An Early Description
 R. Travers, R. Allen.........822
Correspondence
Septic Abscess in a Child with JIA Receiving
Anti-TNF-a Therapy
P.G. Fitch, R.Q . Cron.........825
Reply
P.P. Kaur, C.T. Derk, M. Chatterji,
R.J. Dehoratius.........826
Hypothyroidism Contributes to Increased
Triglyceride Levels Among Patients with SSc
P.J. Kotyla, M. Lewicki, E.J. Kucharz.........827
Reply
M. Kodera, S. Sato.........827
Letter
Fibromyalgia Is a Neuropathic Pain Syndrome
M. Martinez-Lavin.........827
Corrections
Effect of Inflammatory Activity and Glucorticoid
Use on Nutritional Variables in Patients with
Juvenile Idiopathic Arthritis
L. Souza, S.H. Machado, M. Bredemeier,
J.C.T. Brenol, R.M. Xavier.........829
An Evidence-Based Approach to Prescribing Nonsteroidal Antiinflammatory Drugs
H. Tannenbaum, C. Bombardier, P. Davis,
A.S. Russell.........829
Meetings in Rheumatology
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