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VOLUME 29: NO. 8 AUGUST 2002
Editorials
Another Selective COX-2 Inhibitor:
More Questions Than Answers

R.O. Day .........1581
The Concept of Disease Modification in Spondyloarthropathy
 H. Marzo-Ortega, P. Emery, D. McGonagle .........1583
Monitoring MTX Hepatic Toxicity in RA: Is It Time to Update the Guidelines?
 Y. Yazici, D. Erkan, S.A. Paget .........1586
Not Yet Time to Change the Guidelines for
Monitoring MTX Liver Toxicity: They Have
Served Us Well
 J.M. Kremer .........1590
Articles
Modifications in Adenoviral Coat Fiber Proteins and Transcriptional Regulatory Sequences Enhance Transgene Expression

H. Perlman, H. Liu, C. Georganas, et al .........1593
Suppressive Effect of Hochu-Ekki-To on Collagen Induced Arthritis in DBA1J Mice

L.X. Hai, T. Kogure, A. Niizawa, et al .........1601
Antirheumatic Effects of Humanized Anti-Fas Monoclonal Antibody in Human RA/SCID Mouse Chimera
 H. Matsuno, K. Yudoh, F. Nakazawa, et al .........1609
Hyperhomocysteinemia in RA: Influence of MTX Treatment and Folic Acid Supplementation

O.K. Jensen, C. Rasmussen, F. Mollerup, et al .........1615
Cardiovascular Risk Factors in Chilean Patients
with RA
 M. Cisternas, M.A. Gutiérrez, J. Klaassen,
A.M. Acosta, S. Jacobelli .........1619
A Randomized, Controlled, Clinical Trial of
Etoricoxib in the Treatment of RA

A.K. Matsumoto, A. Melian, D.R. Mandel, et al .........1623
Effectiveness Profiles and Dose Dependent
Retention of Traditional DMARD for RA.
An Observational Study

D. Aletaha, J.S. Smolen .........1631
MTX, Hydroxychloroquine, and Intramuscular
Gold in RA: Relative Area Under the Curve Effectiveness and Sequence Effects
 S. Hurst, M.J. Kallan, F.J. Wolfe, J.F. Fries,
D.A. Albert .........1639
Amelioration of Accelerated Collagen Induced
Arthritis by a Novel Calcineurin Inhibitor, ISATX247

W.P. Maksymowych, G.S. Jhangri,
L. Aspeslet, et al .........1646
High Dose Chemotherapy and Hematopoietic Stem Cell Transplantation: A Study of Treatment Preference in Patients with RA and Rheumatologists
 R.J. Verburg, S.D. Mahabali, A.M. Stiggelbout,
J.K. Sont, J.M. van Laar .........1653
Infusion of Epinephrine Decreases Serum Levels of Cortisol and 17-Hydroxyprogesterone in
Patients with RA
 R.H. Straub, J.M. Kittner, C. Heijnen,
M. Schedlowski, R.E. Schmidt, R. Jacobs .........1659
Screening for Hydroxychloroquine Toxicity by Texas Ophthalmologists

P.H. Blomquist, R.K. Chundru .........1665
Macrophage Migration Inhibitory Factor Gene Polymorphism Is Associated with Sarcoidosis in Biopsy Proven Erythema Nodosum
 M.M. Amoli, R.P. Donn, W. Thomson, et al .........1671
SLE Disease Severity in Men and Women:
A Case-Control Study

C. Aranow, J. Del Guidice, P. Barland,
A. Weinstein .........1674
Role of DNA Methylation in Transcription of
Human Endogenous Retrovirus in the
Pathogenesis of SLE
 M. Okada, H. Ogasawara, H. Kaneko, et al .........1678
Factor V Leiden, Prothrombin Gene Mutation,
and Thrombosis Risk in Patients with
Antiphospholipid Antibodies
 N. Chopra, S. Koren, W.L. Greer, et al .........1683
Behçet's Disease in Southern Chinese Patients
 C.C. Mok, T.C. Cheung, C.T.K. Ho, K.W. Lee,
C.S. Lau, R.W.S. Wong .........1689
Trends in the Incidence of PMR over a 30 Year Period in Olmsted County, Minnesota, USA

M.F. Doran, C.S. Crowson, W.M. O'Fallon,
G.G. Hunder, S.E. Gabriel .........1694
Myofibroblast Accumulation Correlates with the Formation of Fibrotic Tissue in a Rat Air Pouch Model

A. Bjärdahlen, P-O. Önnervik, G. Westergren-Thorsson,
A. Malmström, B. Särnstrand .........1698
Cetylated Fatty Acids Improve Knee Function in Patients with OA
 R. Hesslink Jr, D. Armstrong III, M.V. Nagendran,
S. Sreevatsan, R. Barathur .........1708
Joint Space Narrowing and Relationship with Symptoms and Signs in Adults Consulting for
Hip Pain in Primary Care

S.M.A. Bierma-Zeinstra, J.D. Oster, R.M.D. Bernsen,
J.A.N. Verhaar, A.Z. Ginai, A.M. Bohnen .........1713
A Cross Sectional Study of the Association
Between Sex, Smoking, and Other Lifestyle
Factors and OA of the Hand
 G. Jones, H.M. Cooley, J.M. Stankovich .........1719
IL-17 Induced NO Suppresses Matrix Synthesis and Protects Cartilage from Matrix Breakdown

L. Cai, P. Suboc, D.A. Hogue, D.T.W. Fei,
E.H. Filvaroff .........1725
Therapeutic Exercise for People with OA of the Hip or Knee. A Systematic Review

M. Fransen, S. McConnell, M. Bell .........1737
Cartilage Intermediate Layer Protein Expression in Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

K. Yamakawa, H. Iwasaki, I. Masuda, et al .........1746
Validation of the Arabic Version of the WHO-ILAR
COPCORD Core Questionnaire for Community Screening of Rheumatic Diseases in Kuwaitis

A. Al-Awadhi, S. Olusi, M. Moussa, et al .........1754
Physically Demanding Situations as Predictors of Disability Pensioning with Soft Tissue Rheumatism Among Persons 3039 Years Old in Norway, 1981-90
 H.H. Holte, K. Tambs, T. Bjerkedal .........1760
Pediatric Rheumatology
Severe Cardiac Involvement in Children with
SSc and Myositis

P. Quartier, D. Bonnet, J-C. Fournet, et al .........1767
Synovial Membrane Expression of MMP and Tissue Inhibitor 1 in Juvenile Idiopathic Arthritides

M. Gattorno, V. Gerloni, A. Morando, et al .........1774
Juvenile Onset Ankylosing Spondylitis (JAS) Has Less Severe Spinal Disease Course Than Adult Onset Ankylosing Spondylitis (AAS): Clinical Comparison Between JAS and AAS in Korea

H.J. Baek, K.C. Shin, Y.J. Lee, et al .........1780
Changes in Markers of Bone Turnover and Inflammatory Variables During Alendronate Therapy
in Pediatric Patients with Rheumatic Diseases

R. Cimaz, M. Gattorno, M.P. Sormani, et al .........1786
Case Reports
Gynecomastia and Sexual Impotence Associated with MTX Treatment

M.A. Aguirre, A. Vélez, M. Romero, E. Collantes .........1793
Necrotizing Granulomatous Vasculitis Associated with Cocaine Use
 E. Gertner, D. Hamlar .........1795
Images in Rheumatology
Subcutaneous Tophaceous Nodule Formation Due to Deposition of Cholesterol Crystals

J.T. Kelley III, C. Agudelo .........1798
Correspondence
Identification of Radiologic Healing Phenomena in Patients with RA A. Larsen .........1800
Reply R. Rau, S. Wassenberg, G. Herborn .........1800
Cauda Equina Syndrome or a Complication of
Total Hip Arthroplasty?
E. Gilgil, T. Tuncer, M.I. Arman .........1801
Reply M. Harth, K.P. White .........1801
Coexistent Sickle Cell Disease and JRA: 2 Cases with Delayed Diagnosis and Severe Destructive Arthropathy
B.A. Eberhard .........1802
Reply K.J. Murray, K. Nistala .........1802
Sjögren's Syndrome Associated T Cell Large Granular Lymphocyte Leukemia: A Possible Common Etiopathogenesis G. Coakley .........1803
Reply Y. Molad, E. Okon, P. Stark, M. Prokocimer .........1803
Letters
Basal Levels of DHEAS as a Marker for Disease
Activity in Premenopausal Women with
Recent Onset RA
B. Josipovic, A. Josipovic .........1803
Total Plasma Homocysteine Is Not Increased in Japanese Patients with Gout Z. Tsutsumi, Y. Moriwaki,
T. Yamamoto, S. Takahashi, T. Hada .........1805
Alopecia Areata in a Patient with RA Treated with Leflunomide
J-E. Gottenberg, P-Y. Venancie, X. Mariette .........1806
Captopril Induced Lupus N.B. Ratliff III .........1807
Is Fibrillin-1 the Link Between AS and Marfan's Syndrome? P. Fietta, P. Manganelli .........1808
Hemarthrosis and Scurvy I. Haslock .........1808
Notices
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