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VOLUME 29: NO. 8 AUGUST 2002

Editorials

Another Selective COX-2 Inhibitor: More Questions Than Answers

R.O. Day .........1581

The Concept of Disease Modification in Spondyloarthropathy

H. Marzo-Ortega, P. Emery, D. McGonagle .........1583

Monitoring MTX Hepatic Toxicity in RA: Is It Time to Update the Guidelines?

Y. Yazici, D. Erkan, S.A. Paget .........1586

Not Yet Time to Change the Guidelines for Monitoring MTX Liver Toxicity: They Have Served Us Well

J.M. Kremer .........1590

Articles

Modifications in Adenoviral Coat Fiber Proteins and Transcriptional Regulatory Sequences Enhance Transgene Expression
 
H. Perlman, H. Liu, C. Georganas, et al .........1593

Suppressive Effect of Hochu-Ekki-To on Collagen Induced Arthritis in DBA1J Mice
 
L.X. Hai, T. Kogure, A. Niizawa, et al .........1601

Antirheumatic Effects of Humanized Anti-Fas Monoclonal Antibody in Human RA/SCID Mouse Chimera
 
H. Matsuno, K. Yudoh, F. Nakazawa, et al .........1609

Hyperhomocysteinemia in RA: Influence of MTX Treatment and Folic Acid Supplementation
 
O.K. Jensen, C. Rasmussen, F. Mollerup, et al .........1615

Cardiovascular Risk Factors in Chilean Patients with RA
 
M. Cisternas, M.A. Gutiérrez, J. Klaassen, A.M. Acosta, S. Jacobelli .........1619

A Randomized, Controlled, Clinical Trial of Etoricoxib in the Treatment of RA
 
A.K. Matsumoto, A. Melian, D.R. Mandel, et al .........1623

Effectiveness Profiles and Dose Dependent Retention of Traditional DMARD for RA. An Observational Study
 
D. Aletaha, J.S. Smolen .........1631

MTX, Hydroxychloroquine, and Intramuscular Gold in RA: Relative Area Under the Curve Effectiveness and Sequence Effects
 
S. Hurst, M.J. Kallan, F.J. Wolfe, J.F. Fries, D.A. Albert .........1639

Amelioration of Accelerated Collagen Induced Arthritis by a Novel Calcineurin Inhibitor, ISATX247
 
W.P. Maksymowych, G.S. Jhangri, L. Aspeslet, et al .........1646

High Dose Chemotherapy and Hematopoietic Stem Cell Transplantation: A Study of Treatment Preference in Patients with RA and Rheumatologists
 
R.J. Verburg, S.D. Mahabali, A.M. Stiggelbout, J.K. Sont, J.M. van Laar .........1653

Infusion of Epinephrine Decreases Serum Levels of Cortisol and 17-Hydroxyprogesterone in Patients with RA
 
R.H. Straub, J.M. Kittner, C. Heijnen, M. Schedlowski, R.E. Schmidt, R. Jacobs .........1659

Screening for Hydroxychloroquine Toxicity by Texas Ophthalmologists
 
P.H. Blomquist, R.K. Chundru .........1665

Macrophage Migration Inhibitory Factor Gene Polymorphism Is Associated with Sarcoidosis in Biopsy Proven Erythema Nodosum
 
M.M. Amoli, R.P. Donn, W. Thomson, et al .........1671

SLE Disease Severity in Men and Women: A Case-Control Study
 
C. Aranow, J. Del Guidice, P. Barland, A. Weinstein .........1674

Role of DNA Methylation in Transcription of Human Endogenous Retrovirus in the Pathogenesis of SLE
 
M. Okada, H. Ogasawara, H. Kaneko, et al .........1678

Factor V Leiden, Prothrombin Gene Mutation, and Thrombosis Risk in Patients with Antiphospholipid Antibodies
 
N. Chopra, S. Koren, W.L. Greer, et al .........1683

Behçet's Disease in Southern Chinese Patients
 
C.C. Mok, T.C. Cheung, C.T.K. Ho, K.W. Lee, C.S. Lau, R.W.S. Wong .........1689

Trends in the Incidence of PMR over a 30 Year Period in Olmsted County, Minnesota, USA
 
M.F. Doran, C.S. Crowson, W.M. O'Fallon, G.G. Hunder, S.E. Gabriel .........1694

Myofibroblast Accumulation Correlates with the Formation of Fibrotic Tissue in a Rat Air Pouch Model
 
A. Bjärdahlen, P-O. Önnervik, G. Westergren-Thorsson, A. Malmström, B. Särnstrand .........1698

Cetylated Fatty Acids Improve Knee Function in Patients with OA
 
R. Hesslink Jr, D. Armstrong III, M.V. Nagendran, S. Sreevatsan, R. Barathur .........1708

Joint Space Narrowing and Relationship with Symptoms and Signs in Adults Consulting for Hip Pain in Primary Care
 
S.M.A. Bierma-Zeinstra, J.D. Oster, R.M.D. Bernsen, J.A.N. Verhaar, A.Z. Ginai, A.M. Bohnen .........1713

A Cross Sectional Study of the Association Between Sex, Smoking, and Other Lifestyle Factors and OA of the Hand
 
G. Jones, H.M. Cooley, J.M. Stankovich .........1719

IL-17 Induced NO Suppresses Matrix Synthesis and Protects Cartilage from Matrix Breakdown
 
L. Cai, P. Suboc, D.A. Hogue, D.T.W. Fei, E.H. Filvaroff .........1725

Therapeutic Exercise for People with OA of the Hip or Knee. A Systematic Review
 
M. Fransen, S. McConnell, M. Bell .........1737

Cartilage Intermediate Layer Protein Expression in Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
 
K. Yamakawa, H. Iwasaki, I. Masuda, et al .........1746

Validation of the Arabic Version of the WHO-ILAR COPCORD Core Questionnaire for Community Screening of Rheumatic Diseases in Kuwaitis
 
A. Al-Awadhi, S. Olusi, M. Moussa, et al .........1754

Physically Demanding Situations as Predictors of Disability Pensioning with Soft Tissue Rheumatism Among Persons 30­39 Years Old in Norway, 1981-90
 
H.H. Holte, K. Tambs, T. Bjerkedal .........1760

Pediatric Rheumatology

Severe Cardiac Involvement in Children with SSc and Myositis
 
P. Quartier, D. Bonnet, J-C. Fournet, et al .........1767

Synovial Membrane Expression of MMP and Tissue Inhibitor 1 in Juvenile Idiopathic Arthritides
 
M. Gattorno, V. Gerloni, A. Morando, et al .........1774

Juvenile Onset Ankylosing Spondylitis (JAS) Has Less Severe Spinal Disease Course Than Adult Onset Ankylosing Spondylitis (AAS): Clinical Comparison Between JAS and AAS in Korea
 
H.J. Baek, K.C. Shin, Y.J. Lee, et al .........1780

Changes in Markers of Bone Turnover and Inflammatory Variables During Alendronate Therapy in Pediatric Patients with Rheumatic Diseases
 
R. Cimaz, M. Gattorno, M.P. Sormani, et al .........1786

Case Reports

Gynecomastia and Sexual Impotence Associated with MTX Treatment
 
M.A. Aguirre, A. Vélez, M. Romero, E. Collantes .........1793

Necrotizing Granulomatous Vasculitis Associated with Cocaine Use
 
E. Gertner, D. Hamlar .........1795

Images in Rheumatology

Subcutaneous Tophaceous Nodule Formation Due to Deposition of Cholesterol Crystals

J.T. Kelley III, C. Agudelo .........1798

Correspondence

Identification of Radiologic Healing Phenomena in Patients with RA A. Larsen .........1800

Reply R. Rau, S. Wassenberg, G. Herborn .........1800

Cauda Equina Syndrome or a Complication of Total Hip Arthroplasty? E. Gilgil, T. Tuncer, M.I. Arman .........1801

Reply M. Harth, K.P. White .........1801

Coexistent Sickle Cell Disease and JRA: 2 Cases with Delayed Diagnosis and Severe Destructive Arthropathy B.A. Eberhard .........1802

Reply K.J. Murray, K. Nistala .........1802

Sjögren's Syndrome Associated T Cell Large Granular Lymphocyte Leukemia: A Possible Common Etiopathogenesis G. Coakley .........1803

Reply Y. Molad, E. Okon, P. Stark, M. Prokocimer .........1803

Letters

Basal Levels of DHEAS as a Marker for Disease Activity in Premenopausal Women with Recent Onset RA B. Josipovic, A. Josipovic .........1803

Total Plasma Homocysteine Is Not Increased in Japanese Patients with Gout Z. Tsutsumi, Y. Moriwaki, T. Yamamoto, S. Takahashi, T. Hada .........1805

Alopecia Areata in a Patient with RA Treated with Leflunomide J-E. Gottenberg, P-Y. Venancie, X. Mariette .........1806

Captopril Induced Lupus N.B. Ratliff III .........1807

Is Fibrillin-1 the Link Between AS and Marfan's Syndrome? P. Fietta, P. Manganelli .........1808

Hemarthrosis and Scurvy I. Haslock .........1808

Notices



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