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Editorials

WOMAC: A 20-Year Experiential Review of a Patient-Centered Self-Reported Health Status Questionnaire

N. Bellamy .........2473

The Hand: A Second Face?

E.R. Bogoch, M.G.P. Judd .........2477

Pharmacogenetics for the Individualization of Treatment of Rheumatic Disorders Using Azathioprine

E.G. Seidman, D.E. Furst .........2484

Articles

Metacarpophalangeal Arthroplasty in RA: What Determines Satisfaction with Surgery?
 
L.A. Mandl, D.H. Galvin, J.P. Bosch, et al .........2488

Adverse Effects of Sulfasalazine in Patients with RA Are Associated with Diplotype Configuration at the N-Acetyltransferase 2 Gene
 
E. Tanaka, A. Taniguchi, W. Urano, et al .........2492

Expression Analysis of the Glucocorticoid Receptor and Nuclear Factor-kB Subunit p50 in Lymphocytes from Patients with RA
 
M. Eggert, A. Klüter, D. Rusch, et al .........2500

Practical Pharmacogenetics: The Cost Effectiveness of Screening for Thiopurine s-Methyltransferase Polymorphisms in Patients with Rheumatological Conditions Treated with Azathioprine
 
C.A. Marra, J.M. Esdaile, A.H. Anis .........2507

Autoantibodies in Early Seropositive RA, Before and During Disease Modifying Antirheumatic Drug Treatment
 
H.E. Paulus, J. Wiesner, K.J. Bulpitt, et al .........2513

Contemporary Disease Modifying Antirheumatic Drugs (DMARD) in Patients with Recent Onset RA in a US Private Practice: MTX as the Anchor Drug in 90% and New DMARD in 30% of Patients
 
T. Sokka, T. Pincus .........2521

The Use of Infliximab in Academic Rheumatology Practice: an Audit of Early Clinical Experience
 
M-A. Fitzcharles, D. Clayton, H.A. Ménard .........2525

Antiphospholipid Antibodies and Incidence of Venous Thrombosis in a Cohort of Patients with SLE
 
E. Somers, L.S. Magder, M. Petri .........2531

Expression of Cyclin B1 and Cyclin Dependent Kinase Inhibitor p21 in Lymphocytes in Patients with SLE
 
C-Y. Ho, C-K. Wong, E.K-M. Li, L-S. Tam, C.W-K. Lam .........2537

Defining Lupus Cases for Clinical Studies: The Boston Weighted Criteria for the Classification of SLE
 
K.H. Costenbader, E.W. Karlson, M.H. Liang, L.A. Mandl .........2545

Prevalence of Factors Influencing Cancer Risk in Women with Lupus: Social Habits, Reproductive Issues, and Obesity
 
S. Bernatsky, J-F. Boivin, L. Joseph, et al .........2551

Specific Antibody Response After Influenza Immunization in SLE
 
M. Abu-Shakra, J. Press, N. Varsano, et al .........2555

Upregulated Expression of Transforming Growth Factor-ß Receptors in Dermal Fibroblasts of Skin Sections from Patients with Systemic Sclerosis
 
M. Kubo, H. Ihn, K. Yamane, K. Tamaki .........2558

Increased Circulating Concentrations of the Counteradhesive Proteins SPARC and Thrombospondin-1 in Systemic Sclerosis (Scleroderma). Relationship to Platelet and Endothelial Cell Activation
 
R.F. Macko, A.C. Gelber, B.A. Young, et al .........2565

Risk of Ovarian Failure and Fertility After IV Cyclophosphamide. A Study in 84 Patients
 
D. Le Thi Huong, Z. Amoura, P. Duhaut, et al .........2571

Inflammatory Joint Manifestations Are Prevalent in Psoriasis: Prevalence Study of Joint and Axial Involvement in Psoriatic Patients, and Evaluation of a Psoriatic and Arthritic Questionnaire
 
G-M. Alenius, B. Stenberg, H. Stenlund, M. Lundblad, S. Rantapää Dahlqvist .........2577

Dutch Patients with Familial and Sporadic AS Do Not Differ in Disease Phenotype
 
M. van der Paardt, B. Dijkmans, E. Giltay, I. van der Horst-Bruinsma .........2583

Supplementary Vitamin E Does Not Affect the Loss of Cartilage Volume in Knee OA: A 2 Year Double Blind Randomized Placebo Controlled Study
 
A.E. Wluka, S. Stuckey, C. Brand, F.M. Cicuttini .........2585

Comparison of a Computer Based Method and the Classical Manual Method for Radiographic Joint Space Width Assessment in Hip OA
 
J.F. Maillefert, J.T. Sharp, L.S. Aho, M. Dougados .........2592

Radiographic Methods in Knee OA: A Further Comparison of Semiflexed (MTP), Schuss-Tunnel, and Weight-Bearing Anteroposterior Views for Joint Space Narrowing and Osteophytes
 
F. Wolfe, N.E. Lane, C. Buckland-Wright .........2597

Interleukin 17, a Nitric Oxide-Producing Cytokine with a Peroxynitrite-Independent Inhibitory Effect on Proteoglycan Synthesis
 
S. Pacquelet, N. Presle, C. Boileau, et al .........2602

Are There Distinctive Inflammatory Flares After Hylan G-F 20 Intraarticular Injections?
 
S. Pullman-Mooar, P. Mooar, M. Sieck, G. Clayburne, H.R. Schumacher .........2611

The Determinants of Change in Patella Cartilage Volume in Osteoarthritic Knees
 
F. Cicuttini, A. Wluka, Y. Wang, S. Stuckey .........2615

The Effects of Exercise and Education, Individually or Combined, in Women with FM
 
S.J. King, J. Wessel, Y. Bhambhani, D. Sholter, W. Maksymowych .........2620

Stochastic Processes in the Causation of Rheumatic Disease
 
P.J. Roberts-Thomson, M.E. Jones, J.G. Walker, J.G. Macfarlane, M.D. Smith, M.J. Ahern .........2628

Pediatric Rheumatology

Longterm Followup of Childhood Lupus Nephritis
 
S. Hagelberg, Y. Lee, J. Bargman, et al .........2635

Aerobic Fitness in Children with JIA: A Systematic Review
 
T. Takken, A. Hemel, J. van der Net, P.J.M. Helders .........2643

Chronic Arthritis Associated with Chromosome Deletion 22q11.2 Syndrome
 
P. Pelkonen, P. Lahdenne, R. Lantto, V. Honkanen .........2648

Case Reports

Churg-Strauss Syndrome in a Group of Patients Receiving Fluticasone for Asthma
 
S.M. Cooper, B.S. Libman, M. Lazarovich .........2651

Brachial Plexopathy as a Presenting Symptom of GCA
 
I.A. Chowdhry, J. Sinha, P. Barland .........2653

Images in Rheumatology

The Role of Cardiac MRI in APS

D. Erkan, H. Erel, Y. Yazici, M.R. Prince .........2658

Eosinophilia, Arthritis, and Soft Tissue Swellings

M.J. Bridges, C. Holland .........2660

Correspondence

Use of Prognostic Markers to Guide Biologic Therapies for RA C.A. D'Arcy, R.F. Willkens .........2662

Reply J. Listing, R. Rau .........2662

Removal of Hyaline Articular Cartilage Reduces Lymphocyte Infiltration and Activation in Rheumatoid Synovial Membrane K. Fujii .........2663

Reply Y.T. Konttinen .........2663

Should We Be Reading This Journal? G.M. Papadimitriou .........2664

Reply M.B. Stanbrook .........2664

Letters

False Positive Elevation of Cardiac Troponin I in Seropositive RA S. Bas, S. Genevay, N. Mensi .........2665

Antineutrophil Cytoplasmic Antibodies - A "Red Flag" in Patients with SSc S. Casari, M. Haeney, S. Farrand, A. Herrick .........2666

Book Review

Whiplash and Other Useful Illnesses .........2667

Correction

Health and Functional Status of Twins with Chronic Regional and Widespread Pain L.A. Aaron, L.M. Arguelles, S. Ashton, et al .........2667

Notices