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VOLUME 29: NO. 1 JANUARY 2002

Editorials

Splenectomy Has a Limited Role in the Management of Lupus with Thrombocytopenia

D. Alarcón .........1

PPARg Ligands as Modulators of Inflammatory and Catabolic Responses in Arthritis. An Overview

H. Fahmi, J-P. Pelletier, J. Martel-Pelletier .........3

Articles

Collagenase-1 (MMP-1) and HLA-DRB1 Gene Polymorphisms in RA: A Prospective Longitudinal Study
 
A. Constantin, V. Lauwers-Cancès, F. Navaux, et al .........15

Effects of Gold on Cytokine Production in Vitro; Increase of Monocyte Dependent IL-10 Production and Decrease of IFN-g Levels
 
J. Lampa, L. Klareskog, J. Rönnelid .........21

Tumor Necrosis Factor-a Gene Polymorphism in Severe and Mild­Moderate RA
 
M. Fabris, E. Di Poi, A. D'Elia, G. Damante, L. Sinigaglia, G. Ferraccioli .........29

Expression and Localization of Vascular Endothelial Growth Factor-C in RA Synovial Tissue
 
K. Wauke, M. Nagashima, T. Ishiwata, G. Asano, S. Yoshino .........34

Vascular Endothelial Growth Factors C and D and their VEGFR-2 and 3 Receptors in Blood and Lymphatic Vessels in Healthy and Arthritic Synovium
 
K. Paavonen, J. Mandelin, T. Partanen, et al .........39

Effects of Dexamethasone on Lymphocyte Proliferation and Cytokine Production in RA
 
S.R. De Antonio, H.M. Blotta, R.L. Mamoni, et al .........46

A Population Based Assessment of the Use of Orthopedic Surgery in Patients with RA
 
L. Massardo, S.E. Gabriel, C.S. Crowson, W.M. O'Fallon, E.L. Matteson .........52

Altered Levels of Soluble Adhesion Molecules in Patients with RA Complicated by Peripheral Neuropathy
 
Y.M. El Miedany, S. Ashour, H. Moustafa, I. Ahmed .........57

Occurrence of Extraarticular Disease Manifestations Is Associated with Excess Mortality in a Community Based Cohort of Patients with RA
 
C. Turesson, W.M. O'Fallon, C.S. Crowson, S.E. Gabriel, E.L. Matteson .........62

A Critical Evaluation of Enzyme Immunoassay Kits for Detection of Antinuclear Autoantibodies of Defined Specificities. II. Potential for Quantitation of Antibody Content
 
E.M. Tan, J.S. Smolen, J.S. McDougal, et al .........68

Treatment of Severe Immune Thrombocytopenia Associated with SLE: 59 Cases
 
C. Arnal, J-C. Piette, J. Léone, et al .........75

The Effect of High Salt Concentration on Detection of Serum Immune Complexes and Autoantibodies to Clq in Patients with SLE
 
J. Kohro-Kawata, M.H. Wener, M. Mannik .........84

High Prevalence of Autoantibodies Against the Nuclear High Mobility Group (HMG) Protein SSRP1 in Sera from Patients with SLE, But Not Other Rheumatic Diseases
 
P. Santoro, M. De Andrea, G. Migliaretti, C. Trapani, S. Landolfo, M. Gariglio .........90

Enhanced Expression of the Receptor for Granulocyte Macrophage Colony Stimulating Factor on Dermal Fibroblasts from Scleroderma Patients
 
L. Postiglione, S. Montagnani, A. Riccio, et al .........94

Ulnar Artery Involvement in Systemic Sclerosis (Scleroderma)
 
M.H. Taylor, J.A. McFadden, M.B. Bolster, R.M. Silver .........102

Gelatinase Expression and Activity in the Synovium and Skin of Patients with Erosive PsA
 
C.A. Hitchon, C.L. Danning, G.G. Illei, H.S. El-Gabalawy, D.T. Boumpas .........107

Successful Short Term Treatment of Severe Undifferentiated SpA with the Anti-TNF-a Monoclonal Antibody Infliximab
 
J. Brandt, H. Haibel, J. Reddig, J. Sieper, J. Braun .........118

Evidence for Synovitis in Active PMR: Sonographic Study in a Large Series of Patients
 
P. Falsetti, B. Frediani, L. Storri, et al .........123

Minimal Clinically Important Rehabilitation Effects in Patients with OA of the Lower Extremities
 
F. Angst, A. Aeschlimann, B.A. Michel, G. Stucki .........131

The Longterm Outcome of OA: Rates and Predictors of Joint Space Narrowing in Symptomatic Patients with Knee OA
 
F. Wolfe, N.E. Lane .........139

A Cartilage Derived Novel Compound DDP (2, 6-dimethyldifuro-8-pyrone): Isolation, Purification, and Identification
 
H.K. Gahunia, A. Lough, R. Vieth, K.P.H. Pritzker .........147

Novel Fluorescent Compound (DDP) in Calf, Rabbit, and Human Articular Cartilage and SF
 
H.K. Gahunia, R. Vieth, K.P.H. Pritzker .........154

Absence of Linkage or Association for OA with the Vitamin D Receptor/Type II Collagen Locus: The Framingham OA Study
 
C.T. Baldwin, L.A. Cupples, O. Joost, et al .........161

Pediatric Rheumatology

Lack of Association Between JIA and Fas Gene Polymorphism
 
R. Donn, E. Zeggini, E. Shelley, W. Ollier, W. Thomson, and The British Paediatric Rheumatology Study Group .........166

Sleep and Its Relationship to Pain, Dysfunction, and Disease Activity in JRA
 
B.J. Bloom, J.A. Owens, M. McGuinn, C. Nobile, L. Schaeffer, A.J. Alario .........169

A Prospective Population Based Study on Outcome of JCA in Costa Rica
 
O. Arguedas, A. Fasth, B. Andersson-Gäre .........174

Rheumatic Manifestation of Bartonella Infection in 2 Children
 
M.J. Al-Matar, R.E. Petty, D.A. Cabral, et al .........184

Neonatal Lupus Manifests as Isolated Neutropenia and Mildly Abnormal Liver Functions
 
S. Kanagasegar, R. Cimaz, B.T. Kurien, A. Brucato, R.H. Scofield .........187

Case Reports

Leflunomide Induced Fevers, Thrombocytosis, and Leukocytosis in a Patient with Relapsing Polychondritis
 
A.S. Koenig, J.L. Abruzzo .........192

Bone Marrow Necrosis and Refractory HELLP Syndrome in a Patient with Catastrophic Antiphospholipid Antibody Syndrome
 
J. Sinha, I. Chowdhry, S. Sedan, P. Barland .........195

Images in Rheumatology

Alkaptonuria with Atypical Joint Involvement

A. Alrehaily, J.E. Pope .........198

Correspondence

Identity of the Joint Lubricant
B.A. Hills .........200

Reply
G.D. Jay .........201

Letters

Beneficial Effect of Being Outdoors in RA
W.R. Patberg, J.J. Rasker .........202

Monoarthritis as Presenting Sign of Stress Fracture
C. Garcia-Porrua, J.V. Andion, M.A. Gonzalez-Gay .........204

Corrections

Improved Functional Ability in Patients with Rheumatoid Arthritis — Longterm Treatment with Leflunomide Versus Sulfasalazine
J.R. Kalden, D.L. Scott, J.S. Smolen, et al, for the European Leflunomide Study Group .........205

Total Hip Arthroplasty in Ankylosing Spondylitis: Outcome in 340 Patients
S. Sweeney, R. Gupta, G. Taylor, A. Calin .........205

Notices

© 2002. The Journal of Rheumatology Publishing Company Limited. All rights reserved.