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VOLUME 31: NO. 3 MARCH 2004

Editorials

Clinical Trials, Outcome Measures, and Response Criteria
 
S.R. Pillemer, B. Tilley .........407

Defining Therapeutic Success in Rheumatoid Arthritis Clinical Trials: From Statistical Significance to Clinical Significance
 
A. Maetzel .........411

Suboptimal Osteoporosis Management: Moving Beyond Detection
 
T. Neogi, J.J. Allison .........413

Hepatitis C and B Cells: Induction of Autoimmunity and Lymphoproliferation May Reflect Chronic Stimulation Through Cell-Surface Receptors
 
G. Starkebaum, E.H. Sasso .........416

Estrogen Metabolites: Increasing Evidence for Their Role in Rheumatoid Arthritis and Systemic Lupus Erythematosus
 
M. Cutolo .........419

Articles

Polymorphism in Promoter Region of IL10 Gene Is Associated with RA in Women
   
L. Padyukov, A-M. Hytönen, M. Smolnikova, et al 422

TNF-a Promotes the Expression of Osteoprotegerin in Rheumatoid Synovial Fibroblasts
   
A. Kubota, K. Hasegawa, T. Suguro, Y. Koshihara .........426

Erythromycin Suppresses the Expression of Cyclooxygenase-2 in Rheumatoid Synovial Cells
   
T. Fumimori, S. Honda, K. Migita, et al .........436

Polymorphisms in the MBL Gene Are Not Associated with Radiographic Erosions in Rheumatoid or Inflammatory Polyarthritis
   
A. Barton, H. Platt, F. Salway, et al .........442

Expression of IL-12R and IL-18R on CD4+ T Cells from Patients with RA
   
T. Aita, M. Yamamura, M. Kawashima, et al .........448

Immune Activation and Depression in Women with RA
   
A.J. Zautra, D.C. Yocum, I. Villanueva, et al .........457

Role of mRNA Expression of Transcription Factors in Glucocorticoid Sensitivity of Peripheral Blood Mononuclear Cells and Disease State in RA
   
K. Onda, E. Rimbara, T. Hirano, et al .........464

Patient Retention and Hand-Wrist Radiograph Progression of RA During a 3-Year Prospective Study That Prohibited DMARD
   
H.E. Paulus, D. Di Primeo, J.T. Sharp, et al .........470

Autologous Hemopoietic Stem Cell Transplantation in Severe RA: A Report from the EBMT and ABMTR
   
J.A. Snowden, J. Passweg, J.J. Moore, et al .........482

Patients with RA and SLE Have Increased Renal Excretion of Mitogenic Estrogens in Relation to Endogenous Antiestrogens
   
C. Weidler, P. Härle, J. Schedel, M. Schmidt, J. Schölmerich, R.H. Straub .........489

Triple Association Between Hepatitis C Virus Infection, Systemic Autoimmune Diseases, and B Cell Lymphoma
   
M. Ramos Casals, O. Trejo, M. Garcia-Carrasco, et al .........495

Autoantibodies Against a-Fodrin in SS with Neurological Manifestations
   
J. de Seze, S. Dubucquoi, A-L. Fauchais, et al .........500

Sensitivity and Specificity for Primary SS of IgA and IgG Anti-a-Fodrin Antibodies Detected by ELISA
   
A. Ruffatti, P. Ostuni, P. Grypiotis, et al .........504

Erectile Dysfunction Associated with Scleroderma: A Case-Control Study of Men with Scleroderma and RA
   
P. Hong, J.E. Pope, J.M. Ouimet, E. Rullan, J.R. Seibold .........508

Elevated Circulating CD40L Concentrations in Patients with SSc
   
K. Komura, S. Sato, M. Hasegawa, M. Fujimoto, K. Takehara .........514

Geographical and Genetic Factors Do Not Account for Significant Differences in the Clinical Spectrum of GCA in Southern Europe
   
M.A. Gonzales-Gay, L. Boiardi, C. Garcia-Porrua, P. Macchioni, J.C. Amor-Dorado, C. Salvarani .........520

Uveitis as the Initial Clinical Manifestation in Patients with SpA
   
J. Fernández-Melón, S. Muñoz-Fernández, V. Hidalgo, et al .........524

Reactive Arthritis Following an Outbreak of Campylobacter jejuni Infection
   
T. Hannu, M. Kauppi, M. Tuomala, I. Laaksonen, P. Klemets, M. Kuusi .........528

Successful Short Term Treatment of Patients with Severe Undifferentiated Spondyloarthritis with the Anti-TNF-a Fusion Receptor Protein Etanercept
   
J. Brandt, A. Khariouzov, J. Listing, et al .........531

A Portable Digital Microphotography Unit for Rapid Documentation of Periungual Nailfold Capillary Changes in Autoimmune Connective Tissue Diseases
   
R.D. Sontheimer .........539

The Cervical Spine in Calcium Pyrophosphate Dihydrate Deposition Disease. A Prevalent Case-Control Study
   
A. Finckh, D. Van Linthoudt, B. Duvoisin, P. Bovay, J-C. Gerster .........545

Multifaceted Educational Program Increases Prescribing of Preventive Medication for Corticosteroid Induced Osteoporosis
   
M. Naunton, G.M. Peterson, G. Jones, G.M. Griffin, M.D. Bleasel .........550

Lubricating Ability of Aspirated Synovial Fluid from Emergency Department Patients with Knee Joint Synovitis
   
G.D. Jay, K.A. Elsaid, J. Zack, et al .........557

Efficacy and Safety of 5% Ibuprofen Cream Treatment in Knee OA. Results of a Randomized, Double-Blind, Placebo-Controlled Study
   
K. Trnavský, M. Fischer, U. Vögtle-Junkert, F. Schreyger .........565

Hospital, Pharmacy, and Outpatient Costs for OA and Chronic Back Pain
   
D.W. Mapel, M. Shainline, K. Paez, M. Gunter .........573

Lyon Schuss Radiographic View of the Knee. Utility of Fluoroscopy for the Quality of Tibial Plateau Alignment
   
T. Conrozier, P. Mathieu, M. Piperno, et al .........584

Are Preferences for Cyclooxygenase-2 Inhibitors Influenced by the Certainty Effect?
   
L. Fraenkel, D.R. Wittink, J. Concato, T. Fried .........591

Prevalence of Rheumatic Diseases in Brazil: A Study Using the COPCORD Approach
   
É.R. Senna, A.L.P. De Barros, E.O. Silva, et al .........594

Clues to Pathogenesis of FM in Patients with Sickle Cell Disease
   
N. Schlesinger .........598

Historical Vignette Professor Eric Bywaters, 1910-2003. Memories of Taplow
 
H.A. Smythe .........601

Pediatric Rheumatology

MHC Class I Overexpression on Muscles in Early JDM
   
C.K.C. Li, H. Varsani, J.L. Holton, B. Gao, P. Woo, L.R. Wedderburn .........605

Decreased Pain Threshold in Children with Growing Pains
   
P.J. Hashkes, O. Friedland, L. Jaber, H.A. Cohen, B. Wolach, Y. Uziel .........610

Case Reports

Circulating VEGF Concentrations in a Case of Pulmonary Hypertrophic Osteoarthropathy. Correlation with Disease Activity
   
F. Olán, M. Portela, C. Navarro, el al .........614

Unusual Differential Diagnosis of a Swollen Toe
   
M. Wahle, C.G.O. Baerwald .........617

Images in Rheumatology

DISH: Isolated Involvement of Cervical Spine in a Young Patient
 
R. Mader .........620

Arthritis Induced by Corticosteroid Crystals
 
E. Selvi, R. De Stefano, S. Lorenzini, R. Marcolongo .........622

Correspondence

Macrophage Activation Syndrome and Etanercept in Children with Systemic JRA H. Sarwar, L.R. Espinoza, A. Gedalia .........623

Reply A.V. Ramanan, R. Schneider .........623

Therapeutic Implications for Interferon-a in Arthritis I. Kötter, N. Stübiger .........624

Reply E.N. Fish .........624

Letter

False Positive Parvovirus Serology A.H. Johnson, A. Gough .........625

Notices



Return to March 2004 Table of Contents



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