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VOLUME 33: NO. 3 MARCH 2006
Editorials
Outcome Issues for Rheumatoid Arthritis: What Do We Have and What Do We Want?
 D.A. Albert .........441
Management of Whiplash-Associated Disorders Revisiting Quebec
 R. Ferrari .........443
The Role of Inflammatory Cytokines in the Pathogenesis of Systemic Lupus Erythematosus-Related Atherosclerosis: A Novel Target for Treatment?
 O. Shovman, B. Gilburd, Y. Shoenfeld .........445
Quantitative Clinical Rheumatology Saving Time and Improving Care with a Multidimensional Health Assessment Questionnaire: 10 Practical Considerations
 T. Pincus, Y. Yazici, M. Bergman.........448
Articles
Effects of Viral IL-10 Introduced by in vivo Electroporation on Arthrogen-Induced Arthritis in Mice
 T. Kuroda, H. Maruyama, M. Shimotori, et al .........455
Simvastatin Inhibits Production of IL-6 and IL-8 and Cell Proliferation Induced by TNF-a in Fibroblast-like Synoviocytes from Patients with RA
 K. Yokota,
T. Miyazaki, M. Hirano, Y. Akiyama, T. Mimura .........463
Quinacrine But Not Chloroquine Inhibits PMA Induced Upregulation of MMP in Leukocytes: Quinacrine Acts at the Transcriptional Level Through a PLA2-Independent Mechanism
 K.M. Stuhlmeier, C. Pollaschek.........472
Splitting High-Dose Oral MTX Improves Bioavailability: A Pharmacokinetic Study in Patients with RA
 M. Hoekstra, C. Haagsma, C. Neef, J. Proost,
A. Knuif, M. van de Laar.........481
Combination of Cyclosporine and Leflunomide versus Single Therapy in Severe RA
 G. Karanikolas,
D. Charalambopoulos, A. Andrianakos, C. Antoniades,
N. Katsilambros.........486
Short-term Outcome After Anti-TNF-a Therapy in RA: Do We Need to Revise Our Assessment Criteria?
 Y. El Miedany, S.S. Youssef, M. El Gaafary .........490
Anti-CCP Antibodies as a Predictor of Response to Anti-TNF-a Therapy in Patients with RA
 Y. Braun-Moscovici, D. Markovits, O. Zinder, et al .........497
Minimal Clinically Important Difference in Radiological Progression of Joint Damage. A Definition Based on Patient Perspective
 P.M.J. Welsing, G.F. Borm, P.L.C.M. van Riel .........501
Loss of Cortical Bone from the Metacarpal Diaphysis
in Patients with RA: Independent Effects of Systemic Inflammation and Glucocorticoids
 J.F. Roldán, I. del Rincón, A. Escalante.........508
Cervical Spine Surgery in Patients with RA:
Longterm Mortality and Its Determinants
 A. Ronkainen, M. Niskanen, A. Auvinen, J. Aalto,
R. Luosujärvi .........517
Polymorphism of the FcgRIIa IgG Receptor in
Patients with Lupus Nephritis and Glomerulopathy
 A.P. Gelmetti, A.C. Freitas, V. Woronik, R.T. Barros,
E. Bonfá, R.C. Monteiro.........523
Prevalence of Neurocognitive Dysfunction and Other Clinical Manifestations in Disabled Patients with SLE
 T.O. Utset, J. Fink, N.A. Doninger.........531
Increased Concentration of Proatherogenic Inflammatory Cytokines in SLE: Relationship to Cardiovascular Risk Factors
 Y. Asanuma, C.P. Chung, A. Oeser, et al .........539
Proton MRS Reveals Central Neuroaxonal
Impairment in SSc
 L. Bertinotti, M. Mortilla, M.L. Conforti, et al .........546
Developing Classification Criteria for Peripheral
Joint PsA. Step I. Establishing Whether the Rheumatologist's Opinion on the Diagnosis Can
Be Used as the "Gold Standard"
 D.P.M. Symmons, M. Lunt, G. Watkins, et al.........552
Prospective Observational Analysis of the Efficacy
and Safety of Low-Dose (3 mg/kg) Infliximab in AS:
4-Year Followup
 S. Keeling, A. Oswald, C. Mallon,
A.S. Russell, W.P. Maksymowych.........558
Medication Errors with the Use of Allopurinol and Colchicine: A Retrospective Study of a National, Anonymous Internet-Accessible Error Reporting System
 T.R. Mikuls, J.R. Curtis, J.J. Allison,
R.W. Hicks, K.G. Saag .........562
Pennsaid® Therapy for OA of the Knee: A Systematic Review and Metaanalysis of Randomized Controlled Trials
 T.E. Towheed.........567
Measurement of Pain Using the Visual Numeric
Scale
 P.L. Ritter, V.M. González, D.D. Laurent, K.R. Lorig .........574
Assessing a Whiplash Management Model:
A Population-Based Non-Randomized
Intervention Study
 S. Suissa, M. Giroux, M. Gervais, et al.........581
Utilization and Cost Comparison of Current and Optimal Prescribing of NSAID in Quebec, Canada
 E. Rahme, Y. Toubouti, J. Lelorier.........588
Pediatric Rheumatology
Comparison of Clinical and Laboratory Variables in Familial versus Sporadic Systemic Onset JIA
 S.M. Al-Mayouf, S.M. Madi, K. Almane,
S. Al Jummah.........597
Effect of Inflammatory Activity and Glucocorticoid
Use on Nutritional Variables in Patients with JIA
 L. Souza, S.H. Machado, M. Bredemeier, J.C.T. Brenol,
R.M. Xavier .........601
Treatment of Pediatric Localized Scleroderma
with MTX

P.G. Fitch, P. Rettig, J.M. Burnham, et al .........609
Chondrocyte Apoptosis and Expression of Bcl-2, Bax, Fas, and iNOS in Articular Cartilage in Patients with Kashin-Beck Disease
 S.J. Wang, X. Guo, H. Zuo, et al .........615
Case Reports
Laser Induced Chrysiasis: Disfiguring Hyperpigmentation Following Q-Switched Laser Therapy in a Woman Previously Treated with Gold

H. Almoallim, A.V. Klinkhoff, A.B. Arthur, J.K. Rivers,
A. Chalmers .........620
Pulmonary Complications of Infliximab Therapy in Patients with RA
 A.J.K. Östör, E.R. Chilvers,
M.F. Somerville, et al.........622
Pantoprazole and pANCA-Associated Vasculitis
 D. Jacobs-Kosmin, C.T. Derk, N. Sandorfi .........629
Images in Rheumatology
Supernumerary Metatarsal Bone
 F. Borraccia, M. Montaruli, G. Peruz, I. Olivieri .........633
Obituary Morris Ziff, 1913-2005
 H.E. Jasin.........634
Morris Ziff On a personal note
 A.S. Russell.........635
Correspondence
Nonsystemic Vasculitic Neuropathy:
A Clinicopathological Study of 22 Cases
P.M. Aries, W.L. Gross.........636
Reply
E. Kararizou.........636
Letter
Bilateral Ocular Myositis as a Late Complication of Dermatomyositis
D.T.L. Liu, A.Y.K. Chan.........637
Meetings in Rheumatology.........
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