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OMERACT
8
International
Consensus Conference on Outcome Measures in Rheumatology Clinical
Trials, St. Julian's Bay, Malta, May 10-14, 2006
Introduction

M.
Boers, V. Strand, L.S. Simon, P. Tugwell, P. Brooks .........599
Biomarkers
and Surrogate Endpoints
The
WHO
International Classification of Functioning, Disability and Health: A
Conceptual Model and Interface for the OMERACT Process

G.
Stucki, A. Boonen, P. Tugwell, A. Cieza, M. Boers .........600
Definitions
and Validation Criteria for Biomarkers and Surrogate Endpoints:
Development and Testing of a Quantitative Hierarchical Levels of
Evidence Schema

M.N.
Lassere, K.R. Johnson, M. Boers, et al .........607
Simulation
Studies of Surrogate Endpoint Validation Using Single Trial and
Multitrial Statistical Approaches

M.
Lassere, K. Johnson, M. Hughes, et al .........616
Synovial
Macrophages as a Biomarker of Response to Therapeutic Intervention in
RA: Standardization and Consistency Across Centers

B.
Bresnihan, D.M. Gerlag, T. Rooney, et al .........620
Testing
of
the Preliminary OMERACT Validation Criteria for a Biomarker to Be
Regarded as Reflecting Structural Damage Endpoints in RA Clinical
Trials: The Example of CRP

S.O.
Keeling, R. Landewé, D. van der Heijde, et al .........623
Development
of Draft Validation Criteria for a Soluble Biomarker to Be Regarded
as a Valid Biomarker Reflecting Structural Damage Endpoints in RA and
SpA Clinical Trials

W.P.
Maksymowych, R. Landewé, M. Boers, et al .........634
Assessing
Single Joints in Arthritis Clinical Trials

J.T.
Giles, P. Mease, M. Boers, et al .........641
Imaging
Summary
Findings of a Systematic Review of the Ultrasound Assessment of
Synovitis

F. Joshua, M. Lassere, G.A. Bruyn, et al
.........839
The
OMERACT
Ultrasound Group: Status of Current Activities and Research
Directions

R.J. Wakefield, M-A. D'Agostino, A. Iagnocco,
et al .........848
The
OMERACT
MRI Inflammatory Arthritis Group Advances and Priorities

M.
Østergaard, F. McQueen, P. Bird, et al
.........852
A
Multireader
Reliability Study Comparing Conventional High-Field MRI with
Extremity Low-Field MRI in RA

P. Bird, B. Ejbjerg, M.
Lassere, et al .........854
A
Multicenter
Reliability Study of Extremity-MRI in the Longitudinal Evaluation of
RA

P.G. Conaghan, B. Ejbjerg, M. Lassere, et al
.........857
Developing
a
MRI Scoring System for Peripheral Psoriatic Arthritis

F.
McQueen, M. Lassere, P. Bird, et al .........859
Scoring
Inflammatory Activity of the Spine by MRI in AS: A Multireader
Experiment

C. Lukas, J. Braun, D. van der Heijde, et al
.........862
Is
There a
Preferred Method for Scoring Activity of the Spine by MRI in AS?
 D.
van der Heijde, R. Landewé, K-G. Hermann, et al
.........871
Computer
Based Methods for Measurement of Joint Space Width: Update of an
Ongoing OMERACT Project

J.T. Sharp, J. Angwin, M. Boers,
et al .........874
Repair
in RA,
Current Status. Report of a Workshop at OMERACT 8

D. van
der Heijde, R. Landewé, J.T. Sharp for the OMERACT
Subcommittee on Repair .........884
Outcome
Measures
Outcome
Measures in PsA

D.D.
Gladman, P.J. Mease, P. Healy, et al .........1159
Consensus
on
a Core Set of Domains for PsA

D.D.
Gladman, P.J. Mease, V. Strand, et al .........1167
Patient
Perspective: Reasons and Methods for Measuring Fatigue in RA

J.R.
Kirwan, S. Hewlett .........1171
Patient
Perspective: Fatigue as a Recommended Patient Centered Outcome
Measure in RA

J.R.
Kirwan, P. Minnock, A. Adebajo, et al.........1174
Considerations
and Preliminary Proposals for Defining a Reference Case for Economic
Evaluations in AS

N.
Bansback, A. Maetzel, M. Drummond, et al .........1178
Rationale
and
Strategies for Reevaluating the ACR20

D.T.
Felson, D.E. Furst, M. Boers.........1184
Minimal
Clinically Important Improvement and Patient Acceptable Symptom State
for Subjective Outcome Measures in Rheumatic Disorders

F.
Tubach, P. Ravaud, D. Beaton, et al .........1188
SSc
—
Continuing Progress in Developing Clinical Measures of Response

D.
Furst, D. Khanna, M. Matucci-Cerinic, et al .........1194
Workshops
and
Special Interest Groups
The
Future of
Damage Assessment in Vasculitis

P.
Seo, R.A. Luqmani, O. Flossmann, et al.........1357
Worker
Productivity Outcome Measures in Arthritis

R.
Escorpizo, C. Bombardier, A. Boonen, et al.........1372
Outcome
Evaluations in Gout

H.R.
Schumacher, W. Taylor, N. Joseph-Ridge, et al .........1381
Preliminary
Development of a Responder Index for Chronic Low Back Pain

L.S.
Simon, C. Evans, N. Katz, et al.........1386
Development
of the Effective Musculoskeletal Consumer Scale

E.
Kristjansson, P.S. Tugwell, A.J. Wilson, et al.........1392
Standardizing
Assessment and Reporting of Adverse Effects in Rheumatology Clinical
Trials II: the Rheumatology Common Toxicity Criteria v.2.0

T.
Woodworth, D.E. Furst, R. Alten, et al.........1401
Fibromyalgia
Syndrome

P.
Mease, L.M. Arnold, R. Bennett, et al .........1415
Improving
Patient Reported Outcomes Using Item Response Theory and Computerized
Adaptive Testing

E.F.
Chakravarty, J.B. Bjorner, J.F. Fries .........1426
OMERACT/OARSI
Initiative to Define States of Severity and Indication for Joint
Replacement in Hip and Knee OA

L.
Gossec, G. Hawker, A.M. Davis, et al .........1432
Acknowledgment.........1436

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