Table 2. Proposed definition of silicone-related disorder.

Major criteria
Silicone breast implant with local problems including tenderness, capsule formation, change in shape or position, and/or rupture of the envelope
   Chronic fatigue lasting 6 months
Myalgias with tender muscles
Minor criteria
Postexertional symptom exacerbation
Livedo reticularis
Bladder dysfunction including dysuria, frequency, nocturia, hematuria, and interstitial cystitis
Dry eyes and/or mouth
Impaired cognition—short term memory
Paresthesias/neuropathic pain
Unexplained fever intermittently over 3 months
Arthralgia
Lymphadenopathy
Unrefreshing sleep